The study of the Profort probiotic use in the specific prevention of salmonellosis in calves

In order to increase the post-vaccination immune response during vaccination of calves against salmonellosis, a test was carried out with an inactivated emulsified vaccine background use probiotic Profort. The studies were on basis large livestock farm in Voronezh region, unfavorable for salmonellosis calves. Epizootological, clinical, immunological, hematological, molecular genetic research methods used work. Studies have shown that preparation Profort contributed development intense cellular immunity – total number lymphocytes and T-cells by 7.0%, B-cells 2.8%%, phagocytic activity neutrophils - 5.9%, 7.2%, index as well humoral factors BaS 3.0%, LaS 3.0%%, CaS 1.7%, O- H-agglutinins salmonella antigen 1.5 2 times, respectively. increases protective properties helps reduce incidence 13.3%, safety young animals 26.6%. Therefore, optimize probiotic, it is necessary take into account its immunomodulatory effect.